SubjectsGeneral FactsFactsIP FactoidsWeird Facts A substance from fish bladder is used to make wine and beer. By IP Factly - Dec 13, 2016 0 4 Share on Facebook Tweet on Twitter Image credit: Matt From London/CC BY 2.0 Image credit: Matt From London/CC BY 2.0 Isinglass is a substance found in the swim bladders of fish and once dried, it is used in the processing of wine and beer, particularly to make these beverages clearer.